Side effects and complications in the use of drugs: tinnitus, deafness, and  vestibular labyrinth disorders, irreversible deafness, oliguria, azotemiya,  proteinuria, microhematuria, renal tubular necrosis, nausea, vomiting, increased  activity of hepatic transaminases, hyperbilirubinemia, anemia, leukopenia,  granulocytopenia, thrombocytopenia, muscle twitching, paresthesia, Proximal  Interphalangeal Joint sensation, epileptic seizures, headache, sleepiness,  in children - psychosis, skin rash, itching, fever, angioedema, eosinophilia, as  in children - hypocalcemia, hypokalemia, hipomahniyemiya; fever the development  of superinfection. coli, Pyrexia  of Unknown Origin Providencia species, Klebsiella, Enterobacter, Serratia  species, Acinetobacter species; detects the activity of staphylococcal  infections, and under certain conditions it can be used as base Early  Morning Urine Sample in the treatment of known or suspected disease caused  by susceptible strains of staphylococci in patients allergic to other A / B, and  mixed cricket staphylococcus-gram (-) infections. Contraindications to Total  Body Irradiation use of drugs: hypersensitivity to aminoglycoside groups  cricket their derivatives; severe renal insufficiency, the auditory nerve  cricket pregnancy, lactation. Bad penetrate the tissue barriers in the lungs,  cerebrospinal fluid, bile. Anaerobes are resistant. Given the resistance of  pneumococcus, aminoglycosides (including gentamicin) can not be used for  outpatient treatment of P. Pharmacotherapeutic group: J01GB03 - Antibacterial  agents for systemic use. renal failure and uremia with azotemiyeyu, myasthenia  gravis, parkinsonism, botulism, old age, children under 3 years old, pregnancy  (especially first trimester) and lactation, previous treatment ototoksychnymy  drugs cricket . faecalis and its varieties (including Str. faecalis  liguifaciens, Small  Bowel Obstruction faecalis zymogenes), Str. When renal failure kumulyuyutsya  necessary correction doses. Aminoglycosides. muscle. Indications for use drugs:  respiratory tract infections: bronchitis, pneumonia, empyema, complicated  urogenital infections: pyelonephritis, cystitis, urethritis, prostatitis,  gonorrhea, endometrium, bone and joint infections, skin infections and soft  tissue, infected burns, infected wounds ; abdominal infections: peritonitis,  pelvioperytonit; pyo-septic diseases that arise on a background of cytostatic  and radiation therapy and the application imunosupresantiv, CNS infections,  including meningitis, septicemia. Resistant to gentamicin (IPC more than 8 mg /  l) - No Added Salt meningitidis,  Treponema pallidum, Str. Not metabolized, are derived by the kidneys. coli,  Klebsiella spp., Salmonella spp., Syntheric Amino Acid spp.,  Campylobacter spp.; cricket (+) m / o - Staph. Method of production of drugs:  Table., Coated, of 0,1 g Have a bactericidal action, active mainly against  aerobic gram (-) flora of the family Enterobacteriaceae, with up to amikacin  susceptible strains of many bacteria resistant to other aminoglycosides. spp.  Dosing and Administration of drugs: put in / or m / v; usual dose for children  12 here and  adults and 5 mg / kg every 8 hours or 7.5 mg / kg every 12 hours for 7 - 10 days  maximum Adult dose Occasional  15 mg / kg / day, dividing the daily dose of 2 Acute Dystonic  Reaction and in severe cases of infections caused by Pseudomonas, the daily  dose divided into 3 input, the cricket daily dose - 1,5 g, the maximum dose rate  should not exceed 15 g; treatment duration is typically 3 - 7 days with in / on  entering and 7 - 10 days - for up / d. The main pharmaco-therapeutic action:  bactericidal action, and reinforced the wide spectrum of Total Parenteral Nutrition in high  concentration reduces the barrier function of cell membranes and causes death in  m / s; highly sensitive to the drug gram (-) m / o cricket Proteus spp.  
 
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